Zenapro® is a hybrid hernia-repair device that’s constructed of large-pore polypropylene and multiple layers of biologic extracellular matrix. The outer biologic layers are designed to allow organized connective tissue to deposit around the polypropylene mesh. In a study in rats and rabbits, Zenapro was shown to have only minimal adhesions.1
Versatility matters, and Zenapro can be used in multiple planes. Watch it used in two different techniques.
Transversus abdominis muscle release using Zenapro
Dr. Eric Pauli repairs a hernia using transversus abdominis muscle release (TAR) and the Zenapro Hybrid Hernia Repair Device.
Laparoscopic ventral hernia repair using Zenapro
Dr. Bruce Tulloh performs laparoscopic ventral hernia repair and uses Zenapro to reinforce the patient’s abdominal wall.
The way Zenapro is contstructed helps make it so versatile. Zenapro is made of seven layers.
- The first four layers are biologic. They make up the visceral side of the device. These layers are designed to shield the viscera from the polypropylene mesh.
- The fifth layer is a single sheet of large-pore polypropylene mesh.
- The sixth and seventh layers are also biologic. They make up the abdominal-wall side of the device. This side has a rough texture.
When Zenapro is used in an intraperitoneal placement, the side of the graft with four biologic layers should be intentionally placed toward the abdominal cavity. The side with two biologic layers should touch the peritoneum. You can see Dr. Tulloh do this in the laparoscopic ventral hernia video above.
Those biologic layers of Zenapro also add to its versatility. The biologic layers are an extracellular matrix that comes from porcine small intestinal submucosa. This technology acts as a scaffold for the body to grow vascularized tissue.2
Learn more about Zenapro.
Dr. Eric Pauli and Dr. Bruce Tulloh are paid consultants for Cook Medical.
1 Hodde JP, Suckow MD, Johnson C, et al. Histological and adhesiogenic characterization of the Zenapro Hybrid Hernia Repair Device. Int J Surg Open. 2016;5:27-32.
2 Franklin ME Jr, Treviño JM, Portillo G, et al. The use of porcine small intestinal submucosa as a prosthetic material for laparoscopic hernia repair in infected and potentially contaminated fields: long-term follow-up. Surg Endosc. 2008;22(9):1941-1946. Note: The name of our technology changed since this paper was published.