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Instinct Plus® Endoscopic Clipping Device

Get closure.

instict plus

Reengineered for smoother operation and responsive handling,1 the Instinct Plus Endoscopic Clipping Device combines strength2,3 and strong clip retention3 with the simplicity of one-step deployment. The multiple anchoring tips on the clip aid in dragging and holding tissue, and the clip span is adjustable up to 16 mm wide.

Also known as an endoclip, the Instinct Plus Endoscopic Clipping Device is indicated for a variety of endoscopic applications, including defect closure and hemostasis. The updated indications for use also include endoscopic marking, affixing jejunal feeding tubes to the wall of the small bowel, and affixing esophageal self-expanding metal stents to the esophageal wall.


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    Features and benefits

    Strength and security

    • Strong clip retention
    • Multiple anchoring tips on the clip to aid in dragging and holding tissue
    • Clips reinforced with nitinol, a superelastic shape-memory alloy

    Responsive handling

    • Adjustable clip span that opens up to 16 mm wide
    • One-to-one rotation from the handle to the tip
    • Ability to open and close up to five times for repositioning


    • Compatibility with both forward-viewing and side-viewing scopes
    • Indication for defect closure and hemostasis as well as affixing jejunal feeding tubes and esophageal self-expanding metal stents

    Additional resources

    1. Data on file. Force and throw at handle to approximate tissue and to open clip (with tissue) for Instinct generation 2. Test report 800008-35-R. September 13, 2019.
    2. Ponugoti PL, Rex DK. Clip retention rates and rates of residual polyp at the base of retained clips on colorectal EMR sites. Gastrointest Endosc. 2017;85(3):530-534.
    3. Data on file. Deployed tip tissue dislodgement force post procedure (force of clip retention at tissue) and force of clip compression at tissue for Instinct generation 2. Test report 800008-10-R. August 8, 2019.